The most profitable retail business to start in India involves different segments such as food & beverages, automobile, agriculture, home & furnishing, education, apparel & clothing, and beauty & healthcare.

Fabric Store: It is a traditional retail business and the most profitable retail business to start in India. It is easy to start and operate, as it allows you to keep stock of fabric in accordance with customer demand.
Medical Retail Store: The Indian medical industry has an 18% growth rate. With an educational background in medicine, one can start a medicine shop and see it grow quite well. Hence, a medical retail store can also be the most profitable retail business to start in India, with a high rate of return on investment.
Perfume Store: One can start a perfume store at a minimal investment, with a focus on luxury brands as well as domestic brands.
Wine Store: A wine store can serve as a highly lucrative retail opportunity as it serves as a luxury business. However, considerable investment is required to set up a wine store, such as a suitable location, specific licensing, etc.,
Some of the other ideas for the most profitable retail business to start in India are book stores, shoe laundries, cake shops, coffee shops, spa, craft stores, aquariums, crockery stores, florists, pet stores, auto parts store, etc.

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